ALZHEIMER DISEASE

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 Topic              Health diseases 

Prelims 


It is a disease that affects brain and throughout brain develops black spots in brain, that leads to shrinkage of mind. 

Left ( healthy brain); right (Alzheimer brain) with large black gaps where brain has shrunk 


  • In Alzheimer's disease ,tau and another protein called Amyloid- beta built-up into tangle and plaques- known together as aggregates- that causes brain cells to die and lead to brain shrinkage. 
  • Aggregates form in one region then spread throughout the brain, much like how cancer spread. 
  • Alzheimer progression was mainly caused by cluster spreading between different brain regions in a chain reaction. 
  • Tau is one of the two key protein that implicated in the condition. 
Impacts 

  • Alzheimer in turn results in memory loss, personality changes and inability to carryout daily functions.

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